Senior Principal Scientist
Company: Black Enterprise Magazine
Location: Saint Louis
Posted on: February 25, 2021
A Senior Principal Scientist position is available within the Cell
Line Development (CLD) group in BioProcess R&D (BRD). The
successful applicant will be responsible for the development and
characterization of both mammalian and microbial cell lines for the
clinical/ commercial manufacture of recombinant protein and vaccine
products. They will be expected to provide strong technical,
strategic, and organizational leadership, effectively manage a
multi-project development portfolio and make strong technical and
strategic contributions to multi-disciplinary/ cross-functional
development project teams to ensure efficient and timely execution
of CLD deliverables.
The Senior Principal Scientist will be a champion of innovation to
ensure CLD's technology leadership. They will design and drive
changes to CLD technologies, practices and infrastructure to ensure
impactful organizational evolution and continuous technology
improvements. The successful applicant will contribute to the
development of robust, efficient, scalable strategies and
technologies for improving the processes used to derive recombinant
production cell lines, and the requisite productivity, stability
and product quality outcomes.
This successful applicant will work effectively across
organizational boundaries to establish strong working relationships
with CLD "customers" including Research Units and Manufacturing
partners, to promote efficient, integrated technologies and
work-processes and seamless flow of information. This position will
also work closely with the other BioProcess R&D functions to
facilitate the timely delivery of cell lines to meet IND enabling
Reg Tox and clinical supply objectives and will work across sites
to ensure that best practices are employed.
The Senior Principal Scientist will be responsible for planning and
developing a staff of 4-7 scientists. This role requires a highly
motivated individual with the ability to work closely with other
members of a laboratory group and the department in a matrix team
environment, while maintaining a strong, collaborative culture.
This role is responsible for helping to develop CLD staff through
interpersonal connections and mentoring relationships - actively
developing technical skills and identifying development
opportunities so that all staff can grow and succeed.
The Senior Principal Scientist will be responsible for the
preparation and review of internal technical reports and contribute
to Regulatory Filings and responses to Regulatory questions, as
appropriate. The position will also require oral presentations
internally to scientists and management, and external presentations
and publications as appropriate.
Candidate demonstrates a breadth of diverse leadership experiences
and capabilities including: the ability to influence and
collaborate with peers, develop and coach others, oversee and guide
the work of other colleagues to achieve meaningful outcomes and
create business impact.
+ PhD in molecular biology, cellular biology, biochemistry, or
related field and 10+ years of experience, including possible
+ Experience with mammalian cell culture and recombinant protein
+ Strong theoretical understanding and practical experience with
relevant scientific disciplines, particularly molecular biology/
cell biology/ microbiology/ biochemistry and application to
creating and/ or characterizing recombinant mammalian and/or
microbial cell lines.
+ Demonstrated leadership success in both project and people
management and technology transfers.
+ Demonstrated ability to drive for results and lead innovation and
+ Collaborative, team-oriented leadership and management style
+ Applicants should be bright, organized, self-motivated, and
capable of working independently and in a collaborative, multi-site
+ The successful candidate will possess strong oral and written
+ Familiarity with relevant Regulatory Guidance documents and
Regulatory paradigms and procedures.
+ Experience managing a group of scientists is a plus.
**Other Job Details:**
+ Eligible for Relocation Package: YES
+ Eligible for Employee Referral Bonus: YES
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**EEO & Employment Eligibility**
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conditions of employment for all employees and job applicants
without regard to race, color, religion, sex, sexual orientation,
age, gender identity or gender expression, national origin,
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Research and Development
Keywords: Black Enterprise Magazine, St. Louis , Senior Principal Scientist, Other , Saint Louis, Missouri
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