Senior Scientist - Pulmonary and Critical Care
Company: Washington University in St. Louis
Location: Saint Louis
Posted on: April 9, 2021
Senior Scientist - Pulmonary and Critical Care - 50323 Job ID
50323 Location Medical School Full/Part Time Full-Time
Regular/Temporary Regular Job Type/Schedule This position is
full-time and works approximately 40 hours per week. Department
Name/Job Location This position is within the Department of
Internal Medicine, Division of Pulmonary and Critical Care, which
is on the Medical School Campus. Essential Functions POSITION
SUMMARY: This position is responsible for collaborating with the
principal investigator (PI) on the design, conduct and reporting of
research projects. This project concerns drug development for
post-viral lung disease, including influenza and coronavirus
infections, covering the spectrum from progressive respiratory
failure to chronic conditions such as asthma. The project also
extends this issue into cancer models that overlap in epithelial
stem cell biology. The project covers the entire range of drug
discovery and development, but current goals are focused on
pharmacology and toxicology to enable the next step to clinical
application. Activities include studies in mice and rats in vivo to
assess mechanism, pharmacokinetics, and toxicokinetics as well as
working in collaboration with lab members performing medicinal
chemistry, biochemistry, structural and cell biology to define
drug-target interactions and signaling mechanism of action. In
addition, there will be collaboration with CRO- and biotech-based
activities. PRIMARY DUTIES AND RESPONSIBILITIES:
- Collaborates with the PI on the design, conduct and reporting
of research projects.
- Assists with grant preparation and reporting. May submit grant
proposals in rare circumstances with the approval of the PI,
Department Head and Dean.
- Prepares and submits papers on research.
- Develops hypotheses to be tested and ways of testing it.
- Complies with established safety procedures and maintaining
required documentation on laboratory and specimen conditions.
- Manages research projects with other institutions and
investigators. Required Qualifications Ph.D., M.D. or an equivalent
terminal degree and at least three years of postdoctoral
experience. Preferred Qualifications
- Experience in one or more of the following approaches: cell and
molecular assays for RNA and/or protein, conventional and
fluorescence microscopy, flow cytometry, pharmacology and
toxicology using in vitro and in vivo approaches, and mouse models
of viral infection and/or cancer.
- Analytical reasoning and problem-solving skills.
- Demonstrated working knowledge of standard laboratory policies,
procedures and equipment.
- Ability to communicate in oral and written form with all levels
of personnel and technical publications.
- Ability to work well independently or as a team member. Salary
Range The hiring range for this position is $53,830 - $72,675
annually. Pre-Employment Screening All external candidates
receiving an offer for employment will be required to submit to
pre-employment screening for this position. Current employees
applying for a new position within the university may be subject to
this requirement. The screenings will include a criminal background
check and, as applicable for the position, other background checks,
drug screen, employment and education or licensure/certification
verification, physical examination, certain vaccinations and/or
governmental registry checks. All offers are contingent upon
successful completion of required screening. This position works in
a laboratory environment with potential exposure to biological and
chemical hazards. The individual must be physically able to wear
protective equipment and to provide standard care to research
animals. EOE Statement Washington University is an Equal
Opportunity Employer. All qualified applicants will receive
consideration for employment without regard to race, color,
religion, age, sex, sexual orientation, gender identity or
expression, national origin, genetic information, disability, or
protected veteran status.
Keywords: Washington University in St. Louis, St. Louis , Senior Scientist - Pulmonary and Critical Care, Healthcare , Saint Louis, Missouri
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