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Senior Scientist - Pulmonary and Critical Care

Company: Washington University in St. Louis
Location: Saint Louis
Posted on: April 9, 2021

Job Description:

Senior Scientist - Pulmonary and Critical Care - 50323 Job ID 50323 Location Medical School Full/Part Time Full-Time Regular/Temporary Regular Job Type/Schedule This position is full-time and works approximately 40 hours per week. Department Name/Job Location This position is within the Department of Internal Medicine, Division of Pulmonary and Critical Care, which is on the Medical School Campus. Essential Functions POSITION SUMMARY: This position is responsible for collaborating with the principal investigator (PI) on the design, conduct and reporting of research projects. This project concerns drug development for post-viral lung disease, including influenza and coronavirus infections, covering the spectrum from progressive respiratory failure to chronic conditions such as asthma. The project also extends this issue into cancer models that overlap in epithelial stem cell biology. The project covers the entire range of drug discovery and development, but current goals are focused on pharmacology and toxicology to enable the next step to clinical application. Activities include studies in mice and rats in vivo to assess mechanism, pharmacokinetics, and toxicokinetics as well as working in collaboration with lab members performing medicinal chemistry, biochemistry, structural and cell biology to define drug-target interactions and signaling mechanism of action. In addition, there will be collaboration with CRO- and biotech-based activities. PRIMARY DUTIES AND RESPONSIBILITIES:

  • Collaborates with the PI on the design, conduct and reporting of research projects.
  • Assists with grant preparation and reporting. May submit grant proposals in rare circumstances with the approval of the PI, Department Head and Dean.
  • Prepares and submits papers on research.
  • Develops hypotheses to be tested and ways of testing it.
  • Complies with established safety procedures and maintaining required documentation on laboratory and specimen conditions.
  • Manages research projects with other institutions and investigators. Required Qualifications Ph.D., M.D. or an equivalent terminal degree and at least three years of postdoctoral experience. Preferred Qualifications
    • Experience in one or more of the following approaches: cell and molecular assays for RNA and/or protein, conventional and fluorescence microscopy, flow cytometry, pharmacology and toxicology using in vitro and in vivo approaches, and mouse models of viral infection and/or cancer.
    • Analytical reasoning and problem-solving skills.
    • Demonstrated working knowledge of standard laboratory policies, procedures and equipment.
    • Ability to communicate in oral and written form with all levels of personnel and technical publications.
    • Ability to work well independently or as a team member. Salary Range The hiring range for this position is $53,830 - $72,675 annually. Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. Current employees applying for a new position within the university may be subject to this requirement. The screenings will include a criminal background check and, as applicable for the position, other background checks, drug screen, employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening. This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals. EOE Statement Washington University is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, sexual orientation, gender identity or expression, national origin, genetic information, disability, or protected veteran status.

Keywords: Washington University in St. Louis, St. Louis , Senior Scientist - Pulmonary and Critical Care, Healthcare , Saint Louis, Missouri

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